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Cytogenetic Laboratory
2400 North Rockton Avenue,
RMB Suite 408
Rockford,
Illinois
61103
Phone: (815)
971-6426
Fax: (815) 961-1353
Hours: Monday - Friday, 8 a.m. to 5 p.m.
For on-call
services, call (815) 971 - 5000
The Cytogenetic Laboratory is
part of Rockford Health System. It
is located in Rockford -
approximately 20 miles from the southern
Wisconsin border and is 90 miles
northwest of
Chicago.
The Cytogenetic Laboratory
currently serves a nine-county area in
Illinois, Wisconsin and
Iowa It
is accredited by The Joint Commission,
the Clinical Laboratory Improvement Act
(CLIA), and the College of American
Pathologists (CAP) and actively
participates in CAP cytogenetic
proficiency testing.
The Lab offers
full-service genetic testing for:
the determination of genetic
disorders, prenatal diagnosis, detection
of changes that are seen in
malignancies, and chromosome anomalies
that can be determined by fluorescent in
situ hybridization (FISH).
The lab provides:
• rapid turn-around time
• an overall cell culture success
rate of 99 percent
• meticulous analysis of cultured
specimens by ASCP certified
professionals
• interpretation by a
Board-Certified Clinical Cytogeneticist
• Genetic consultation referrals
• final written report including
full interpretation and original
karyotype
• faxed reports
followed by a mailed original
Cancer Genetics
Chromosome Analysis {TAT: 5-8 days}
• Bone Marrow
• Leukemic Bloods
• Solid Tumors
• Lymph Nodes
FISH Analysis {TAT: 2-7 days}
• BCR/abl
{t(9;22) in CML}
• HER-2/neu {Breast cancer}
• MDS Panel {del(5), del(7)}
• Multiple Myeloma Panel {del
(13), t(14;18), t(14;11)}
• PML/RARA {t(15;17})
• UroVysion™ {Bladder Cancer}
Prenatal Genetics
Chromosome Analysis
{TAT: 7-14 days}
• Includes amniotic fluid AFP and
reflexive AChE
FISH Analysis
{TAT: 2-4 days)
Rule out anueploidy for:
• Trisomy 13 (Edwards syndrome)
• Trisomy 18 (Patau syndrome)
• Trisomy 21 (Down syndrome)
• Triploidy
• Turner syndrome
• Klinefelter syndrome (XXY)
Congenital
Disorders
Chromosome Analysis {TAT: 4-10 days}
Cultured Lymphocytes
• Congenital anomalies
• Developmental delays
• Suspected genetic syndromes
•
Carrier status for families or
individuals
• Infertility
• Habitual pregnancy loss
• Gender determination
FISH Analysis {TAT: 4-7 days)
Microdeletion Syndromes
• Confirmation of suspected deletions or
translocations seen on banded
chromosomes
Contiguous Gene Syndromes
• DiGeorge/Velocardiofacial syndrome
• Prader Willi/Angelman (deletion 15q)
Aneuploidy syndromes
• Down syndrome (Trisomy 21)
• Edwards syndrome (Trisomy 18)
• Klinefelter syndrome (XXY)
• Patau syndrome (Trisomy 13)
• Trisomy 16
• Turner syndrome (Monosomy X)
Gender determination
Fetal Loss Genetics
(Products of Conception)
Chromosome Analysis
• To determine chromosome
abnormalities in spontaneous abortions
and fetal death
• Useful to determine cause of
demise and to counsel for recurrence
risk
FISH Analysis
• Paraffin-embedded tissue-block
specimens
• Determination of selected aneuploidy
in fetal loss
• Down syndrome (Trisomy 21)
• All syndromes listed under
Congenital Disorders
Fibroblast Cultures
Chromosome Analysis
• When blood is unavailable
• For the establishment of a cell
line to be sent for DNA or biochemical
testing
•
For the establishment of a cell line to
be frozen in liquid nitrogen for future
use
Cytogenetic Microarray
• Currently available for periperal
blood studies.
• Expansion to other samples/studies
will soon be available.
Billing
Billing is done through the Patient
Accounts Department of Rockford Memorial
Hospital.
Available billing:
1.
Institutional billing
2.
Medicare/Medicaid
3.
Patient insurance
4.
Patient self-pay
Specimen Transport
May be arranged
through the
Cytogenetic Laboratory
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